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Quantitative intravital imaging reveals <i>in vivo</i> dynamics of physiological-stress induced mitophagy

2020-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Mitophagy, the selective recycling of mitochondria through autophagy, is a crucial metabolic process induced by cellular stress, and defects are linked to aging, sarcopenia, and neurodegenerative diseases. To therapeutically target mitophagy, the fundamental in vivo dynamics and molecular mechanisms must be fully understood. Here, we generated mitophagy biosensor zebrafish lines expressing mito...

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Literature Corpus work
64801b61-6503-5887-b2ee-5f0590490b0b
DOI
10.1101/2020.03.26.010405
Open publication

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Quantitative intravital imaging reveals <i>in vivo</i> dynamics of physiological-stress induced mitophagyDOI 10.1101/2020.03.26.010405
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