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Article

Semi-automated quantitation of mitophagy in cells and tissues

13 Dec 2019

Abstract excerpt

Mitophagy is a natural phenomenon and entails the lysosomal degradation of mitochondria by the autophagy pathway. In recent years, the development of fluorescent pH-sensitive mitochondrial reporters has greatly facilitated the monitoring of mitophagy by distinguishing between cytosolic mitochondria or those delivered to acidic lysosomes. We recently published the mito-QC reporter, which consists of a...

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PMID: 31843465
DOI: 10.1016/j.mad.2019.111196

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