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Fast and quantitative mitophagy assessment by flow cytometry using the mito-QC reporter

11 Sept 2024

Abstract excerpt

Mitochondrial quality control is finely tuned by mitophagy, the selective degradation of mitochondria through autophagy, and mitochondrial biogenesis. Removal of damaged mitochondria is essential to preserve cellular bioenergetics and prevent detrimental events such as sustained mitoROS production, pro-apoptotic cytochrome c release or mtDNA leakage. The array of tools available to study mitophagy is very limited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39324068
DOI: 10.3389/fcell.2024.1460061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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