Article

Idiosyncratic variation in the fitness costs of tetracycline-resistance mutations in <i>Escherichia coli</i>

2020-09-12

Abstract excerpt

A bacterium’s fitness relative to its competitors, both in the presence and absence of antibiotics, plays a key role in its ecological success and clinical impact. In this study, we examine whether tetracycline-resistant mutants are less fit in the absence of the drug than their sensitive parents, and whether the fitness cost of resistance is constant or variable across independently derived lines. Tetracycline-re...

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Literature Corpus work: 646c17de-7c64-5643-8d6a-a2f071d02abb
DOI: 10.1101/2020.09.12.294355

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