Article
Phenotypic changes associated with the fitness cost in antibiotic resistant Escherichia coli strains.
Molecular bioSystems - 1 Feb 2016
Suzuki Shingo, Horinouchi Takaaki, Furusawa Chikara
Abstract excerpt
BACKGROUND: the acquisition of antibiotic resistance in bacterial cells is often accompanied with a reduction of fitness in the absence of antibiotics, known as the "fitness cost". The magnitude of this fitness cost is an important biological parameter that influences the degree to which antibiotic resistant strains become widespread. However, the relationship between the fitness cost and comprehensive phenotypic...
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