Article

Fibrosis resolution in the mouse liver: role of Mmp12 and potential role of Calpain 1/2

2022-02-18

Abstract excerpt

Although most work has focused on resolution of collagen ECM, fibrosis resolution involves changes to several ECM proteins. The purpose of the current study was two-fold: 1) to examine the role of MMP12 and elastin; and 2) to investigate the changes in degraded proteins in plasma (i.e., the “degradome”) in a preclinical model of fibrosis resolution. Fibrosis was induced by 4 weeks carbon tetrachloride (CCl 4 ) ex...

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Literature Corpus work: 644df51f-f321-56ad-ac0d-d4cf48193055
DOI: 10.1101/2022.02.15.480540

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