Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of liver fibrosis progression and regression by a serological collagen turnover profile.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jan 2019

Karsdal Morten A, Hjuler Sara T, Luo Yi, Rasmussen Daniel G K, Nielsen Mette J, Holm Nielsen Signe, Leeming Diana J, Goodman Zachary, Arch Robert H, Patel Keyur, Schuppan Detlef

Abstract excerpt

There is a need for noninvasive biomarkers that can identify patients with progressive liver fibrosis and monitor response to antifibrotic therapy. An equally important need is identification of patients with spontaneous fibrosis regression, since they may not need treatment nor be included in clinical studies with fibrosis as end point. Circulating biomarkers, originating from defined fragments of the scar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Biopsy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen

Share to Disease Progression

Share to Fibrosis

Share to Liver Cirrhosis

Share to Phenotype

Source

Identifiers

PMID: 30160980
DOI: 10.1152/ajpgi.00158.2018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of liver fibrosis progression and regression by a serological collagen turnover profile.PMID 30160980Read ↗

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertensionSemantic proximity Read ↗

Transcriptomic signatures of progressive and regressive liver fibrosis and portal hypertensionSemantic proximity Read ↗

Pathobiochemical signatures of cholestatic liver disease in bile duct ligated miceSemantic proximity Read ↗

Decoding Fibrosis: Transcriptomic and Clinical Insights via AI-Derived Collagen Deposition Phenotypes in MASLDSemantic proximity Read ↗

The APRI may be enhanced by the use of the FIBROSpect II in the estimation of fibrosis in chronic hepatitis C.Semantic proximity Read ↗

Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration.Semantic proximity Read ↗

Circulating biomarkers reflecting type III, IV and VI collagen remodeling are present in lung tissue of patients with pulmonary fibrosis and non-fibrotic controlsSemantic proximity Read ↗

The alterations in the extracellular matrix composition guide the repair of damaged liver tissueSemantic proximity Read ↗

The fibroid phenotype of biological naïve patients with rheumatoid arthritis are less likely to respond to anti-IL-6R treatment.Semantic proximity Read ↗

Noninvasive markers of liver fibrosis: on-treatment changes of serum markers predict the outcome of antifibrotic therapy.Semantic proximity Read ↗

Metabolic phenotyping of patients with advanced chronic liver disease for better characterization of cirrhosis regression.Semantic proximity Read ↗

Biomarkers of hepatic fibrosis, fibrogenesis and genetic pre-disposition pending between fiction and reality.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.