Article

Amino acid variants in the HLA-DQA1 and HLA-DQB1 molecules explain the major association of variants with relapse status in pediatric patients with steroid-sensitive nephrotic syndrome

2024-12-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Management of patients with steroid-sensitive nephrotic syndrome (SSNS) is challenging because of frequent relapses. Causal variants in the human leukocyte antigen (HLA) class II region that are associated with relapse remain undetermined. <bold>Methods</bold> We collected a cohort of East Asian individuals comprising 206 pediatric patients with SSNS and 435 heal...

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Literature Corpus work: 6444fbe8-9b40-5bf7-93f0-cd7c50a9f4e7
DOI: 10.21203/rs.3.rs-5123909/v1

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