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Article

HLA-DQA1 and APOL1 as Risk Loci for Childhood-Onset Steroid-Sensitive and Steroid-Resistant Nephrotic Syndrome.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Mar 2018

Adeyemo Adebowale, Esezobor Christopher, Solarin Adaobi, Abeyagunawardena Asiri, Kari Jameela A, El Desoky Sherif, Greenbaum Larry A, Kamel Margret, Kallash Mahmoud, Silva Cynthia, Young Alex, Hunley Tracey E, de Jesus-Gonzalez Nilka, Srivastava Tarak, Gbadegesin Rasheed

Abstract excerpt

BACKGROUND: Few data exist for the genetic variants underlying the risk for steroid-sensitive nephrotic syndrome (SSNS) in children. The objectives of this study were to evaluate HLA-DQA1 and APOL1 variants as risk factors for SSNS in African American children and use classic HLA antigen types and amino acid inference to refine the HLA-DQA1 association. STUDY DESIGN: Case-control study. SETTING & PARTICIPANTS:...

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Source

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Identifiers

PMID: 29277510
DOI: 10.1053/j.ajkd.2017.10.013
PMCID: PMC5828864

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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