Article

Effects of decreased Rac activity and malignant state on oral squamous cell carcinoma

2019-02-04

Abstract excerpt

Rac proteins, members of the Rho family of small GTP-binding proteins, have been implicated in transducing a number of signals for various biological mechanisms, including cell cytoskeleton organization, transcription, proliferation, migration, and cancer cell motility. Among human cancers, Rac proteins are highly activated by either overexpression of the genes, up-regulation of the protein, or by mutations that a...

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Literature Corpus work: 642c900f-acba-558e-9d4b-88ecc7230b54
DOI: 10.1101/540591

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