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Article

Interferon-stimulated gene 15 (ISG15) deficiency in dendritic cells protects against contact hypersensitivity (CHS) inflammation in mouse.

2022-11-22

Abstract excerpt

The role of ISG15 (Interferon-Stimulated Gene 15) is becoming increasingly acknowledged in cancer, pathogen infection and inflammatory immune diseases. ISG15 expression increases in human psoriatic skin, and genetic mutations of ISG15 cause dermatological alterations. Here, we show that ISG15 deficiency leads to reduced inflammation and swelling in a murine model of allergic contact dermatitis (ACD). Bone marrow t...

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Literature Corpus work
641fea79-b703-56b8-9159-ccda4183ea96
DOI
10.22541/au.166911170.08332363/v1
Open publication

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Interferon-stimulated gene 15 (ISG15) deficiency in dendritic cells protects against contact hypersensitivity (CHS) inflammation in mouse.DOI 10.22541/au.166911170.08332363/v1
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