Article
Interferon-stimulated gene 15 (ISG15) deficiency in dendritic cells protects against contact hypersensitivity (CHS) inflammation in mouse.
2022-11-22
Abstract excerpt
The role of ISG15 (Interferon-Stimulated Gene 15) is becoming increasingly acknowledged in cancer, pathogen infection and inflammatory immune diseases. ISG15 expression increases in human psoriatic skin, and genetic mutations of ISG15 cause dermatological alterations. Here, we show that ISG15 deficiency leads to reduced inflammation and swelling in a murine model of allergic contact dermatitis (ACD). Bone marrow t...
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Identifiers and source
- Literature Corpus work
- 641fea79-b703-56b8-9159-ccda4183ea96
- DOI
- 10.22541/au.166911170.08332363/v1
