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Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body

13 Dec 2021

Abstract excerpt

Oocytes spend the majority of their lifetime in a primordial state. The cellular and molecular biology of primordial oocytes is largely unexplored; yet, it is necessary to study them to understand the mechanisms through which oocytes maintain cellular fitness for decades, and why they eventually fail with age. Here, we develop enabling methods for live-imaging-based comparative characterization of Xenopus, mouse...

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PMID: 34897463
DOI: 10.1242/jcs.259394

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