Article
Comparative analysis of human and mouse ovaries across age
2025-03-03
Abstract excerpt
Mouse is a tractable model for human ovarian biology, however its utility is limited by incomplete understanding of how transcription and signaling differ interspecifically and with age. We compared ovaries between species using 3D-imaging, single-cell transcriptomics, and functional studies. In mice, we mapped declining follicle numbers and oocyte competence during aging; in human ovaries, we identified cortical...
Topics
Open a Topic to create a Post that cites this publication.
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Ovarian cancer diagnosis and treatment
- Ovarian function and disorders
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- RNA Research and Splicing
- Single-cell and spatial transcriptomics
- Sperm and Testicular Function
Identifiers and source
- Literature Corpus work
- e5537121-457e-5b26-9e0c-cfd8c0f32c76
- DOI
- 10.1101/2025.02.27.640481