Article

Splicing factor proline- and glutamine-rich (SFPQ) protein causes transcriptional repression of SNAIL to counteract TGF-β signaling

2025-12-02

Abstract excerpt

TGF-β is known to regulate several embryonic and adult signaling pathways. Moreover, this signaling pathway regulates several cellular functions including differentiation, cell division, angiogenesis, hematopoiesis, and cell migration. However, studies suggest that an uncontrolled activation of TGF-β signaling may contribute to many human diseases. Therefore, counter-regulatory mechanism(s) to restrain abrupt TGF-...

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Literature Corpus work: 63b82db2-2a43-58cb-9cd9-d69a879b1ed2
DOI: 10.64898/2025.12.01.691266

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