Article

Enhanced microvasculature formation and patterning in iPSC–derived kidney organoids cultured in physiological hypoxia

2021-12-22

Abstract excerpt

Functional kidney organoids have the potential to be used in implantable kidney grafts for patients with end-stage kidney disease, because they have been shown to self-organize from induced pluripotent stem cells into most important renal structures. To date, however, long-term kidney organoid culture has not succeeded, as nephrons lose their phenotype after approximately 25 days. Furthermore, the renal structures...

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Literature Corpus work: 639b7088-521a-53e1-afca-69d1ef752264
DOI: 10.1101/2021.12.22.473849

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