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Stem cell-derived kidney organoids: engineering the vasculature

5 Dec 2019

Abstract excerpt

Kidney organoids can be generated from human pluripotent stem cells (PSCs) using protocols that resemble the embryonic development of the kidney. The renal structures thus generated offer great potential for disease modeling, drug screening, and possibly future therapeutic application. At the same time, use of these PSC-derived organoids is hampered by lack of maturation and off-target differentiation. Here, we...

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PMID: 31807815
DOI: 10.1007/s00018-019-03401-0

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