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The endothelium, a key actor in organ development and hPSC-derived organoid vascularization

22 May 2020

Abstract excerpt

Over the last 4 decades, cell culture techniques have evolved towards the creation of in vitro multicellular entities that incorporate the three-dimensional complexity of in vivo tissues and organs. As a result, stem cells and adult progenitor cells have been used to derive self-organized 3D cell aggregates that mimic the morphological and functional traits of organs in vitro. These so-called organoids were first...

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PMID: 32443983
DOI: 10.1186/s12929-020-00661-y

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