Article

Long read sequencing reveals novel isoforms and insights into splicing regulation during cell state changes

2021-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Alternative splicing (AS) is a key mechanism underlying cellular differentiation and a driver of complexity in mammalian neuronal tissues. However, understanding of which isoforms are differentially used or expressed and how this affects cellular differentiation remains unclear. Long read sequencing allows full-length transcript recovery and quantification, enabling transcript-level analysis of...

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Literature Corpus work: 6382d64d-8863-56e1-988c-de733e1d29c9
DOI: 10.1101/2021.04.27.441628

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