Article

Dynamic changes in mRNA isoform usage during human retinal organoid development

2025-11-26

Abstract excerpt

<h4>Background</h4> Alternative mRNA splicing is a key mechanism for generating isoform diversity in eukaryotic cells. However, the extent of the splicing changes that occur during complex regulatory processes like neurodevelopment are still incompletely characterized. <h4>Results</h4> We performed nanopore-based long-read RNA sequencing on differentiating human stem cell-derived retinal organoids to identify te...

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Literature Corpus work: df0e8c63-42c8-5e84-b07c-bf7d4e62f459
DOI: 10.1101/2025.11.26.689062

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