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Article

The transposable element environment of human genes is associated with histone and expression changes in cancer.

BMC genomics - 9 Aug 2016

Grégoire Laura, Haudry Annabelle, Lerat Emmanuelle

Abstract excerpt

BACKGROUND: Only 2 % of the human genome code for proteins. Among the remaining 98 %, transposable elements (TEs) represent millions of sequences. TEs have an impact on genome evolution by promoting mutations. Especially, TEs possess their own regulatory sequences and can alter the expression pattern of neighboring genes. Since they can potentially be harmful, TE activity is regulated by epigenetic mechanisms....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27506777
DOI: 10.1186/s12864-016-2970-1
PMCID: PMC4979156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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