Article

TEITbase: a database for transposable element (TE)-initiated transcripts in human cancers

2025-05-23

Abstract excerpt

Transposable elements (TEs) are abundant and play a crucial regulatory role in the human genome. Functioning as alternative promoters, TEs can be reactivated to produce TE-initiated transcripts. In cancer, TE-initiated transcription may upregulate oncogene expression and generate novel tumor-specific antigens, which could serve as potential targets for immunotherapy. However, there remains a lack of comprehensive...

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Literature Corpus work: b42505a4-0c3b-5168-82b6-f9c35a69bfba
DOI: 10.1101/2025.05.19.654796

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