Article

Systematic integration of biomedical knowledge prioritizes drugs for repurposing

2016-11-14

Abstract excerpt

The ability to computationally predict whether a compound treats a disease would improve the economy and success rate of drug approval. This study describes Project Rephetio to systematically model drug efficacy based on 755 existing treatments. First, we constructed Hetionet (neo4j.het.io), an integrative network encoding knowledge from millions of biomedical studies. Hetionet v1.0 consists of 47,031 nodes of 11...

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Identifiers and source

Literature Corpus work: 634ba070-79be-5d00-be64-9c6bee82ab98
DOI: 10.1101/087619

Open publication

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