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Clinical Trial and Ontology-Derived Positive and Negative Benchmark Datasets for Drug Repurposing Across Rare Diseases

2026-06-20

Abstract excerpt

Evaluating the potential applications of a medicine is a fundamental challenge in drug development. There is a lack of standardized, decision-oriented benchmarks that test whether computational models can generalize therapeutic hypotheses across diseases in ways that reflect real-world pharmaceutical investment decision making. To address this gap, we introduce two complementary resources: the Indication Expansion...

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Literature Corpus work
d4f9339a-5ab9-5e20-adfd-0b1be48be448
DOI
10.64898/2026.06.15.732135
Open publication

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Clinical Trial and Ontology-Derived Positive and Negative Benchmark Datasets for Drug Repurposing Across Rare DiseasesDOI 10.64898/2026.06.15.732135
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