Article

DR3E-Net: Drug Repurposing Network Framework Based on Deep Embedding, Differentially Expressed Genes, and Drug Side Effects

2024-06-17

Abstract excerpt

In contrast to traditional de-novo drug discovery, which involves high costs and lengthy development times alongside a high failure rate, drug repurposing (DR) offers a potential solution to these challenges. This study introduces DR3E-Net, an in-silico DR framework that integrates embedded vectors of genetic expression influenced by drugs, differentially expressed genes (DEGs) associated with diseases, and inform...

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Literature Corpus work: e6d05bde-4b0b-55c4-9f6c-0fb133e215ad
DOI: 10.1101/2024.06.15.599138

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