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Article

MiT/TFE (TFEB/TFE3) Pathways in Pulmonary Diseases: Current Evidence and Emerging Mechanisms

2026-02-03

Abstract excerpt

The MiT/TFE family transcription factors play a critical role in regulating lysosomal biogenesis, autophagy, mitochondrial turnover and lipid catabolism by regulating the CLEAR gene network. The dysregulation of MiT/TFE activity has been implicated in the onset and progression of cancer and neurodegeneration but its functions in asso-ciation with pulmonary diseases remain poorly understood. Thus, elucidating the r...

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Literature Corpus work
633f123d-d39d-5e2f-acff-44317fdab4ba
DOI
10.20944/preprints202602.0158.v1
Open publication

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MiT/TFE (TFEB/TFE3) Pathways in Pulmonary Diseases: Current Evidence and Emerging MechanismsDOI 10.20944/preprints202602.0158.v1
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