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TFEB Signalling-Related MicroRNAs and Autophagy

4 Jul 2021

Abstract excerpt

The oncogenic Transcription Factor EB (TFEB), a member of MITF-TFE family, is known to be the most important regulator of the transcription of genes responsible for the control of lysosomal biogenesis and functions, autophagy, and vesicles flux. TFEB activation occurs in response to stress factors such as nutrient and growth factor deficiency, hypoxia, lysosomal stress, and mitochondrial damage. To reach the...

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PMID: 34356609
DOI: 10.3390/biom11070985

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