Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role and Regulatory Mechanism of Transcription Factor EB in Health and Diseases

13 Aug 2021

Abstract excerpt

Transcription factor EB (TFEB) is a member of the microphthalmia-associated transcription factor/transcription factor E (MiTF/TFE) family and critically involved in the maintenance of structural integrity and functional balance of multiple cells. In this review, we described the effects of post-transcriptional modifications, including phosphorylation, acetylation, SUMOylation, and ubiquitination, on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Mast cells and histamine
Share to melanin and skin pigmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34490237
DOI: 10.3389/fcell.2021.667750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role and Regulatory Mechanism of Transcription Factor EB in Health and DiseasesPMID 34490237Read ↗

From the regulatory mechanism of TFEB to its therapeutic implicationsSemantic proximity Read ↗

TFEB; Beyond Its Role as an Autophagy and Lysosomes RegulatorSemantic proximity Read ↗

TFEB Signalling-Related MicroRNAs and AutophagySemantic proximity Read ↗

Transcription factor EB regulates cardiovascular homeostasisSemantic proximity Read ↗

Transcription factor EB: from master coordinator of lysosomal pathways to candidate therapeutic target in degenerative storage diseasesSemantic proximity Read ↗

The Regulation of MiTF/TFE Transcription Factors Across Model Organisms: from Brain Physiology to Implication for NeurodegenerationSemantic proximity Read ↗

Past, present, and future perspectives of transcription factor EB (TFEB): mechanisms of regulation and association with diseaseSemantic proximity Read ↗

MiT/TFE (TFEB/TFE3) Pathways in Pulmonary Diseases: Current Evidence and Emerging MechanismsSemantic proximity Read ↗

The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.Semantic proximity Read ↗

Dissecting the multifaced function of transcription factor EB (TFEB) in human diseases: From molecular mechanism to pharmacological modulationSemantic proximity Read ↗

TFEB Biology and Agonists at a GlanceSemantic proximity Read ↗

Emerging roles and regulation of MiT/TFE transcriptional factorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.