Article

Therapy-related myeloid neoplasms: does knowing the origin help to guide treatment?

2016-12-02

Abstract excerpt

Therapy-related myeloid neoplasms (t-MN) combine t-MDS and therapy related acute myeloid leukemia (t-AML) patients in one entity because of their similar pathogenesis, rapid progression from t-MDS to t-AML, and their equally poor prognosis. Treatment with epipodophyllotoxins like etoposide has been associated with a short interval between treatment and development of t-AML, with fusion oncogenes like KMT2A/MLL-MLL...

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Literature Corpus work: 62fde4ee-7812-545c-a723-07c13e2eec9c
DOI: 10.1182/asheducation.v2016.1.24.088333

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