Article
Therapy-related myeloid neoplasms: pathobiology and clinical characteristics.
British journal of pharmacology - 1 Feb 2011
Sill H, Olipitz W, Zebisch A, Schulz E, Wölfler A
Abstract excerpt
Therapy-related myeloid neoplasms (t-MNs) are serious long-term consequences of cytotoxic treatments for an antecedent disorder. t-MNs are observed after ionizing radiation as well as conventional chemotherapy including alkylating agents, topoisomerase-II-inhibitors and antimetabolites. In addition, adjuvant use of recombinant human granulocyte-colony stimulating factor may also increase the risk of t-MNs. There...
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