Article

Pharmacogenomics in Orofacial Clefts Care: Insights From Whole Genome Sequencing of Case-Parents Trios

2025-07-22

Abstract excerpt

<h4>Background: </h4> /Objectives: Orofacial clefts (OFCs) are among the most common birth defects globally, sometimes exacerbated by adverse drug reactions (ADRs) like corticosteroids and antiepileptics. Comprehending the pharmacogenomic and pharmacogenetic elements that lead to ADRs is essential for enhancing precision medicine and clinical outcomes. This study examines rare genetic variants in drug-metabolizing...

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Literature Corpus work: 62fab563-8860-570e-9019-3fd0a90c4388
DOI: 10.20944/preprints202507.1748.v1

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