Article

Genomic Etiology of Pierre Robin Sequence in Africans with Orofacial Clefts

2025-12-15

Abstract excerpt

<title>Abstract</title> <p> Background Pierre Robin Sequence (PRS), characterized by micrognathia, glossoptosis, airway obstruction, and frequently cleft palate, presents significant clinical and genetic complexity, particularly within African populations, where its genetic etiology remains understudied. This study examines genetic architecture of PRS in a Ghanaian cohort with orofacial clefts (OFCs). Materials...

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Literature Corpus work: 1e05b200-c6ae-5506-bef1-4575075ace1c
DOI: 10.21203/rs.3.rs-8214951/v1

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