Article
Clinically actionable secondary findings in 130 triads from sub-Saharan African families with non-syndromic orofacial clefts.
Molecular genetics & genomic medicine - 1 Oct 2023
Oladayo Abimbola, Gowans Lord Jephthah Joojo, Awotoye Waheed, Alade Azeez, Busch Tamara, Naicker Thirona, Eshete Mekonen A, Adeyemo Wasiu L, Hetmanski Jacqueline B, Zeng Erliang, Adamson Olawale, Adeleke Chinyere, Li Mary, Sule Veronica, Kayali Sami, Olotu Joy, Mossey Peter A, Obiri-Yeboah Solomon, Buxo Carmen J, Beaty Terri, Taub Margaret, Donkor Peter, Marazita Mary L, Odukoya Oluwakemi, Adeyemo Adebowale A, Murray Jeffrey C, Prince Anya, Butali Azeez
Abstract excerpt
INTRODUCTION: The frequency and implications of secondary findings (SFs) from genomic testing data have been extensively researched. However, little is known about the frequency or reporting of SFs in Africans, who are underrepresented in large-scale population genomic studies. The availability of data from the first whole-genome sequencing for orofacial clefts in an African population motivated this...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.