Article

Statins for Heart Failure with Preserved Ejection Fraction: Current Evidence and Perspectives

2024-04-15

Abstract excerpt

Systemic inflammation and coronary microvascular endothelial dysfunction are essential pathophysiological factors in heart failure with preserved ejection fraction (HFpEF) that support the use of statins. The pleiotropic properties of statins, such as anti-inflammatory, antihypertrophic, antifibrotic, and antioxidant effects, are generally accepted and may be beneficial in HF, especially in HFpEF. Numerous observa...

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Literature Corpus work: 62eee27f-8d19-5b43-af4c-58b1ffe0f724
DOI: 10.20944/preprints202404.0913.v1

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