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Article

Heart failure with preserved ejection fraction: A systemic disease linked to multiple comorbidities, targeting new therapeutic options.

Archives of cardiovascular diseases - 1 Dec 2018

Juillière Yves, Venner Clément, Filippetti Laura, Popovic Batric, Huttin Olivier, Selton-Suty Christine

Abstract excerpt

Heart failure is a pathology associated with severe morbidity and mortality. In this large field, heart failure with preserved ejection fraction (HFpEF) appears to be an increasing global health problem; it should be considered as a progressive syndrome, characterized by complex mechanisms of systemic and cardiac adaptation that vary over time, particularly with ageing. Multiple biological phenotypes contribute...

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PMID: 29960837
DOI: 10.1016/j.acvd.2018.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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