Article
New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes.
European heart journal - 21 Oct 2014
Senni Michele, Paulus Walter J, Gavazzi Antonello, Fraser Alan G, Díez Javier, Solomon Scott D, Smiseth Otto A, Guazzi Marco, Lam Carolyn S P, Maggioni Aldo P, Tschöpe Carsten, Metra Marco, Hummel Scott L, Edelmann Frank, Ambrosio Giuseppe, Stewart Coats Andrew J, Filippatos Gerasimos S, Gheorghiade Mihai, Anker Stefan D, Levy Daniel, Pfeffer Marc A, Stough Wendy Gattis, Pieske Burkert M
Abstract excerpt
The management of heart failure with reduced ejection fraction (HF-REF) has improved significantly over the last two decades. In contrast, little or no progress has been made in identifying evidence-based, effective treatments for heart failure with preserved ejection fraction (HF-PEF). Despite the high prevalence, mortality, and cost of HF-PEF, large phase III international clinical trials investigating...
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