Article

Modeling ex vivo tumor-infiltrating lymphocyte expansion from established solid malignancies

2021-02-05

Abstract excerpt

Adoptive transfer of tumor-infiltrating lymphocytes (TIL) elicits the regression of metastatic malignancies, yet a low proportion of patients achieve complete durable responses. The high incidence of relapse in these patients highlights the need to better understand mechanisms of tumor escape from T cell control. While melanoma has provided the foundation for developing TIL therapy, much less is known about TIL ef...

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Literature Corpus work: 62e0d500-3e44-55e7-8d65-3b1edfe2fccb
DOI: 10.1101/2021.02.04.429846

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