Article

Longitudinal modelling reveals widespread non-additive genetic effects underlying developmental plasticity

2025-12-23

Abstract excerpt

<h4>ABSTRACT</h4> Developmental plasticity, or the capacity of genotypes to produce different phenotypes under varying contexts, is poorly characterized in humans. Here we developed a longitudinal variance and a genotype-by-time model able to disentangle genetic effects from between-subject variability. Applied to early growth (infant length and BMI) and cognitive traits (math and reading) of 45,000 to 65,000 ind...

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Literature Corpus work: 62bc2ff7-b293-5db2-8ef7-ee09e97055a6
DOI: 10.64898/2025.12.19.695443

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