Article
Complex genetic dependencies among growth and neurological phenotypes in healthy children: Towards deciphering developmental mechanisms.
PloS one - 1 Jan 2020
Uechi Lisa, Jalali Mahjoubeh, Wilbur Jayson D, French Jonathan L, Jumbe N L, Meaney Michael J, Gluckman Peter D, Karnani Neerja, Sakhanenko Nikita A, Galas David J
Abstract excerpt
The genetic mechanisms of childhood development in its many facets remain largely undeciphered. In the population of healthy infants studied in the Growing Up in Singapore Towards Healthy Outcomes (GUSTO) program, we have identified a range of dependencies among the observed phenotypes of fetal and early childhood growth, neurological development, and a number of genetic variants. We have quantified these...
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