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Article

A novel alkyne cholesterol to trace cellular cholesterol metabolism and localization.

Journal of lipid research - 1 Mar 2014

Hofmann Kristina, Thiele Christoph, Schött Hans-Frieder, Gaebler Anne, Schoene Mario, Kiver Yuriy, Friedrichs Silvia, Lütjohann Dieter, Kuerschner Lars

Abstract excerpt

Cholesterol is an important lipid of mammalian cells and plays a fundamental role in many biological processes. Its concentration in the various cellular membranes differs and is tightly regulated. Here, we present a novel alkyne cholesterol analog suitable for tracing both cholesterol metabolism and localization. This probe can be detected by click chemistry employing various reporter azides. Alkyne cholesterol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24334219
DOI: 10.1194/jlr.D044727
PMCID: PMC3934742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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