Article

Human CYP2C9 metabolism of organophosphorus pesticides and nerve agent surrogates

2025-08-01

Abstract excerpt

Of the Cytochrome P450 enzymes, the CYP2C9 variant is very important and is the cytochrome P450 (CYP) involved in the metabolism of several human drugs where it acts as a natural bioscavenger. Previously, CYP2C9 was demonstrated to remove sulfur from different organophosphorus (OP) pesticides, such as dimethoate, diazinon and parathion. In this study, we have tested the ability of CYP2C9 to degrade other OP compou...

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Literature Corpus work: 628b9930-ee59-5332-9479-52f0a8510a4a
DOI: 10.1101/2025.07.29.667567

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