Article
Caveolin-1 Protects Retinal Ganglion Cells against Acute Ocular Hypertension Injury via Modulating Microglial Phenotypes and Distribution and Activating AKT pathway.
Scientific reports - 6 Sept 2017
Zhang Liwei, Xu Jiazhou, Liu Ran, Chen Wei, Chen Qishan, Hu Wenjie, Zhou Lan, Zhang Ruting, Xu Hongping, Lin Dongyue, Li Xuri, Tang Zhongshu
Abstract excerpt
Glaucoma, a group of eye diseases, causes gradual loss of retinal ganglion cells (RGCs) and ultimately results in irreversible blindness. Studies of the underlying mechanisms of glaucoma and clinical trial are far from satisfactory. Results from a genome-wide association study have suggested that the CAV1/CAV2 locus is associated with glaucoma, but this association and its potential underlying mechanisms need to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.