Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular signaling from microglia impacts macroglia autophagy and neurons survival in glaucoma

8 May 2023

Abstract excerpt

Interactions between microglia and macroglia play important roles in the neurodegeneration of the central nervous system and so is the situation between microglia and Müller cells in retina neurodegenerations like glaucoma. This study focuses on the roles of microglia-derived osteopontin (OPN) in impacting Müller cells and retinal ganglion cells (RGCs). Rat model and cell pressurization culture were used to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connexins and lens biology
Share to Neuroinflammation and Neurodegeneration Mechanisms
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37250793
DOI: 10.1016/j.isci.2023.106839

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular signaling from microglia impacts macroglia autophagy and neurons survival in glaucomaPMID 37250793Read ↗

Interplay between Müller cells and microglia aggravates retinal inflammatory response in experimental glaucomaSemantic proximity Read ↗

The role of Müller glia and microglia in glaucomaSemantic proximity Read ↗

The Dual Role of Macroglia in Glaucoma: Deciphering the Contributions of Astrocytes and Müller Cells to Retinal Neurodegeneration and NeuroprotectionSemantic proximity Read ↗

Caveolin-1 Protects Retinal Ganglion Cells against Acute Ocular Hypertension Injury via Modulating Microglial Phenotypes and Distribution and Activating AKT pathway.Semantic proximity Read ↗

A journey into the retina: Müller glia commanding survival and deathSemantic proximity Read ↗

Glaucoma as a Neurodegenerative Disease Caused by Intrinsic Vulnerability Factors.Semantic proximity Read ↗

AIBP protects retinal ganglion cells against neuroinflammation and mitochondrial dysfunction in glaucomatous neurodegenerationSemantic proximity Read ↗

Microglia respond to elevated intraocular pressure and synapse loss in the visual thalamus in a mouse model of glaucomaSemantic proximity Read ↗

Evaluation of Neuroprotective And Immunomodulatory Properties of Mesenchymal Stem Cells in An Ex-vivo Retinal Explant ModelSemantic proximity Read ↗

NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucomaSemantic proximity Read ↗

PLSCR1 promotes apoptosis and clearance of retinal ganglion cells in glaucoma pathogenesisSemantic proximity Read ↗

OPTN protects retinal ganglion cells and ameliorates neuroinflammation in optic neuropathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.