Article
Environmental Regulation of Toxin Production in <i>Bacillus anthracis</i>
2025-10-07
Abstract excerpt
Pathogenic Bacillus anthracis strains carry two plasmids - pX01, which encodes a tripartite protein exotoxin complex (PA, LF, and EF); and pX02, which encodes a poly-D-gamma-glutamic acid capsule. A multidomain transcription factor, AtxA, regulates the expression of these virulence genes. AtxA has two DNA-binding Helix-Turn-Helix (HTH) domains, two phosphoenolpyruvate:carbohydrate phosphotransferase system regula...
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Identifiers and source
- Literature Corpus work
- 6273ec0b-1480-559a-a47a-fa11f1f69bd7
- DOI
- 10.1101/2025.10.02.679957
