Article
Crystal structure of Bacillus anthracis virulence regulator AtxA and effects of phosphorylated histidines on multimerization and activity.
Molecular microbiology - 1 Feb 2015
Hammerstrom Troy G, Horton Lori B, Swick Michelle C, Joachimiak Andrzej, Osipiuk Jerzy, Koehler Theresa M
Abstract excerpt
The Bacillus anthracis virulence regulator AtxA controls transcription of the anthrax toxin genes and capsule biosynthetic operon. AtxA activity is elevated during growth in media containing glucose and CO(2)/bicarbonate, and there is a positive correlation between the CO(2)/bicarbonate signal, A...
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