Article
Opposing effects of histidine phosphorylation regulate the AtxA virulence transcription factor in Bacillus anthracis.
Molecular microbiology - 1 Feb 2007
Tsvetanova Billyana, Wilson Adam C, Bongiorni Cristina, Chiang Christina, Hoch James A, Perego Marta
Abstract excerpt
Expression of genes for Bacillus anthracis toxin and capsule virulence factors are dependent upon the AtxA transcription factor. The mechanism by which AtxA regulates the transcription of its target genes is unknown. Here we report that bioinformatic analyses suggested the presence in AtxA of two PTS (phosphenolpyruvate : sugar phosphotransferase system) regulation domains (PRD) generally regulated by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
