Article
Control of virulence gene expression in Bacillus anthracis.
Journal of applied microbiology - 1 Aug 1999
Hoffmaster A R, Koehler T M
Abstract excerpt
The atxA gene is an important regulator of virulence gene expression in Bacillus anthracis. atxA positively regulates expression of the three genes encoding the anthrax toxin proteins and at least one gene is required for capsule production. Here we report that an atxA-null mutant exhibits phenotypes unrelated to toxin and capsule synthesis. An atxA-null mutant grows poorly on minimal media and sporulates more...
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