Article

Targeting NMDAR2A: Esketamine's Impact on BV2 Microglial Pro-inflammatory Polarization

2024-10-25

Abstract excerpt

<title>Abstract</title> <p>The polarization of microglia to the pro-inflammatory phenotype plays a crucial role in the initiation and progression of neuroinflammatory diseases, primarily owing to the secretion of pro-inflammatory cytokines that exacerbate damage within the central nervous system (CNS). Investigating the mechanisms underlying the inhibition of microglial pro-inflammatory polarization could be the...

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Literature Corpus work: 625b96b8-abd7-57ed-89c7-b7e2fc1febc2
DOI: 10.21203/rs.3.rs-5313533/v1

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