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Article

Versatile Role of Prokineticins and Prokineticin Receptors in Neuroinflammation

9 Nov 2021

Abstract excerpt

Prokineticins are a new class of chemokine-like peptides involved in a wide range of biological and pathological activities. In particular, prokineticin 2 (PK2), prokineticin receptor 1 (PKR1) and prokineticin receptor 2 (PKR2) play a central role in modulating neuroinflammatory processes. PK2 and PKRs, which are physiologically expressed at very low levels, are strongly upregulated during inflammation and...

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PMID: 34829877
DOI: 10.3390/biomedicines9111648

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