Article

CD4 T cells and neutrophils contribute to epithelial-mesenchymal transition in breast cancer

2023-02-15

Abstract excerpt

<h4>ABSTRACT</h4> Epithelial-mesenchymal transition (EMT) is a central oncogenic mechanism, contributing both to transformation and metastatic dissemination. Inflammation and innate immune cells are known to favor EMT induction, but the role of adaptive immunity still remains unclear. Using an original murine mammary tumor model in immune cell subpopulation depletion experiments, we demonstrated that tumor cells...

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Literature Corpus work: 623abdc9-3552-5128-87b1-3db74d7a76db
DOI: 10.1101/2023.02.15.528594

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