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Article

Phytosesquiterpene lactones deregulate mitochondrial activity and phenotypes associated with triple-negative breast cancer metastasis.

Phytomedicine : international journal of phytotherapy and phytopharmacology - 1 Dec 2024

Cheng Yu-Ting, Chang Dao-Ming, Tung Yi-Chung, Hsiao Pei-Wen, Nakagawa-Goto Kyoko, Shyur Lie-Fen

Abstract excerpt

BACKGROUND: Triple-negative breast cancer (TNBC) recurrence and metastasis are the major causes of failure in TNBC therapy. The difficulties in treating TNBCs may be because of increased cancer cell plasticity that involves the fine-tuning of cellular redox homeostasis, mitochondrial bioenergetics, metabolic characteristics, and the development of cancer stem cells (CSCs). PURPOSE: To investigate the effects and...

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Identifiers

PMID: 39571415
DOI: 10.1016/j.phymed.2024.156226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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